A novel approach to boost anti-tumor immune responses

Novel Therapeutics & Platforms, Immunotherapies & Personalized Vaccines

Pandurangan Vijayanand, PhD (LJI)

Michael Jackson, PhD (SBP)

Immunotherapy is rapidly gaining its place as a mainstream treatment of solid cancers, Nonetheless, less than 30% of patients with lung cancer benefit from this approach. This is the result of large gaps in our knowledge of how immunotherapies work and how to choose the right treatment or treatment combination for a particular patient. Cancer immunotherapy aims to stimulate the patient's immune system to attack and kill tumor cells. Our laboratory identified an important immune cell type and a novel surface target to enhance their anti-tumor function. Here, we team with experts in drug development to identify agents to boost tumor immune responses. Studies in this discovery grant have the potential to identify a new class of immunotherapy drugs for patients with lung cancer.